REFERENCE LIST B

Articles Included in the Review of Studies

Ref #

  1. Alford C, Bhatti JZ, Rombaut NEI, Curran S, Hindmarch I. A comparison of antihistamines using EEG and questionnaire-based assessments. Med Sci Res , 1989; 17: 421-423.
  2. Aso T, et al. Effect of terfenadine, a novel antihistamine, on actual driving performance. Ann Allergy , 1989; 62: 250 (Abstract).
  3. Bateman DN, Chapman PH, Rawlins MD. Lack of effect of astemizole on ethanol dynamics or kinetics. Eur J Clin Pharmacol , 1983; 25: 567-568.
  4. Berlinger WG, Goldberg MJ, Spector R, Chiang C, Ghoneim MM. Diphenhydramine: kinetics and psychomotor effects in elderly women. Clin Pharmacol Ther , 1982; 32: 387-391.
  5. Betts T, Markman D, Debenham S, Mortiboy D, McKevitt T. Effects of two antihistamine drugs on actual driving performance. Br Med J , 1984; 288: 281-282.
  6. Betts T, Kenwood C, Dalby G, Hull B, Wild J. A comparison of the effects of two "non-sedating" antihistamines (terfenadine and cetirizine) on tests of CNS function including driving. J Psychopharmacol , 1989; 3/4: 101P (Abstract).
  7. Bhatti JZ, Hindmarch I. The effects of terfenadine with and without alcohol on an aspect of car driving performance. Clin Exp Allergy , 1989; 19: 609-611.
  8. Biehl B. Effects of azatadine maleate on subjective appraisal and psychomotor functions relevant to driving performance. Curr Med Res Opin , 1979; 6: 62-69.
  9. Blom MW, Bartel PR, Sommers DK, Van der Meyden CH, Becker PJ. The comparison of the effects of multi and single doses of buspirone, chlordiazepoxide and hydroxyzine on psychomotor function and EEG. Fundam Clin Pharmacol , 1992; 6: 5-9.
  10. Bonifazi F, Provinciali L, Antonicelli L, Bilo MB, Pucci S, et al. Comparative study of terfenadine and cetirizine in hay fever: assessment of efficacy and central nervous system effects. J Investig Allergol Clin Immunol , 1995; 5: 40-46.
  11. Borbely AA, Youmbi-Balderer G. Effect of diphenhydramine on subjective sleep parameters and on motor activity during bedtime. Int J Clin Pharmacol Ther Toxicol , 1988; 26: 392-396.
  12. Bradley C.M, Nicholson AN. Effects of a mu-opioid receptor agonist (codeine phosphate) on visuo-motor coordination and dynamic visual acuity in man. Br J Clin Pharmacol, 1986; 22: 507-512.
  13. Bradley CM, et al. Studies on performance with aspirin and paracetamol and with the centrally acting analgesics meptazinol and pentazocine. Eur J Clin Pharmacol , 1987; 32:135-139.
  14. Bradley CM, Nicholson AN. Studies on the central effects of the H1-antagonist, loratadine. Eur J Clin Pharmacol , 1987; 32: 419-421.
  15. Brookhuis KA, de Vries G, de Waard D. Acute and subchronic effects of the H1-histamine receptor antagonist ebastine in 10, 20, and 30 mg dose, and triprolidine 10mg on car driving performance. Br J Clin Pharmacol, 1993; 36: 67-70.
  16. Burns M. A laboratory study of antihistamine and muscle relaxant effects on driving-related skills, with and without alcohol. Alc Drug Traffic Safety - T89 , 1990; T89: 470-474.
  17. Burns M, Moskowitz H. Effects of diphenhydramine and alcohol on skills performance. Eur J Clin Pharmacol , 1980; 17: 259-266.
  18. Burns M, Moskowitz H. Antihistamine effects on performance: comparison of diphenhydramine and terfenadine. Alc Drug Traffic Safety - T92, 1993; T92(Band 3): 585-590.
  19. Burns M, Shanaman JE, Shellenberger CH. A laboratory study of patients with chronic allergic rhinitis: Antihistamine effects on skilled performance. J Allergy Clin Immunol, 1994; 93: 716-724.
  20. Burns M, Wilkinson CJ, Korn S, Raskin S, Owens SC. A double-blind, multiple-dose, crossover, placebo-controlled study to investigate the effects of cyclobenzaprine, diphenhydramine and amitriptyline on driving-related psychomotor skills in elderly volunteers. Final Report for Merck (ME-125), 1998.
  21. Bye C, Dewsbury D, Peck AW. Effects on the human central nervous system of two isomers of ephedrine and triprolidine, and their interaction. Br J Clin Pharmacol, 1974; 1: 71-78.
  22. Bye CE, Claridge R, Peck AW, Plowman F. Evidence for tolerance to the central nervous effects of the histamine antagonist, tripolidine, in man. Eur J Clin Pharmacol, 1977; 12: 181-186.
  23. Caldwell J. Assessing the impact of stressors on performance: observations on levels of analyses. Biol Psychol , 1995; 40: 197-208.
  24. Carruthers SG, Shoeman DW, Hignite CE, Azarnoff DL. Correlation between plasma diphenhydramine level and sedative and antihistamine effects. Clin Pharmacol Ther, 1978; 23: 375-382.
  25. Chapman PH, Rawlins MD. A randomized single-blind study of astemizole and chlorpheniramine in normal volunteers. Br J Clin Pharmacol [BPS Proceedings] , 1982; 13: 593P.
  26. Clarke CH, Nicholson AN. Performance studies with antihistamines. Br J Clin Pharmacol , 1978; 6: 31-35.
  27. Cohen AF, Posner J, Ashby L, Smith R, Peck AW. A comparison of methods for assessing the sedative effects of diphenhydramine on skills related to car driving. Eur J Clin Pharmacol , 1984; 27: 477-482.
  28. Cohen AF, Hamilton M, Philipson R, Peck AW. The acute effects of acrivastine (BW825C), a new antihistamine, compared with triprolidine on measures of central nervous system performance and subjective effects. Clin Pharmacol Ther, 1985; 38: 381-386.
  29. Cohen AF, Hamilton MJ, Peck AW. The effects of acrivastine (BW825C), diphenhydramine and terfenadine in combination with alcohol on human CNS performance. Eur J Clin Pharmacol , 1987; 32: 279-288.
  30. Curran HV, Pooviboonsuk P, Dalton JA, Lader MH. Differentiating the effects of centrally acting drugs on arousal and memory: An event-related potential study of scopolamine, lorazepam, and diphenhydramine. Psychopharmacol, 1998; 135: 27-36.
  31. Day ES, Jones S, Stewart-Jones S. Clemastine on hand-eye coordination and visual function. J Clin Pharmacol , 1972; 12: 240 [Letter].
  32. De Gier JJ, Kuypens L, Nelemans FA. The effects of astemizole on actual car driving and psychomotor performance. Drugs and Driving, 1986; Book: 271-278.
  33. De Roeck, Cluydts R, Herman P. Effects of antihistamines on daytime alertness. J Allergy Clin Immunol, 1990; 85: 179 [Abstract].
  34. Dhorranintra B, Limsuvan S, Bunnag C. Effect of astemizole on psychomotor performance in healthy Thais. Drug Development Res , 1986; 7: 285-290.
  35. Dhorranintra B, Sriprasong T, Limsuvan S, Klyprayong S. A study of CNS-side effects of mequitazine, an H1-specific antihistamine in healthy Thai volunteers. Asian Pac J Allergy Immunol, 1990; 8: 39-44.
  36. Doms M, Vanhulle G, Baelde Y, Coulie P, Dupont P, Rihoux JP. Lack of potentiation by cetirizine of alcohol-induced psychomotor disturbances. Eur J Clin Pharmacol , 1988; 34:619-623.
  37. Englisch W, Rehn D, Schaffler K, Wauschkuhn CH. Effects of dimethindene maleate on psychomotor performance in the oculodynamic test compared with placebo and loratadine. Arzneimittelforschung/Drug Res, 1996; 46: 887-890.
  38. Fine BJ, Kobrick JL, Lieberman HR, Marlowe B, Riley RH, et al. Effects of caffeine or diphenhydramine on visual vigilance. Psychopharmacology, 1994; 114: 223-238.
  39. Fink M, Irwin P. CNS effects of the antihistamines diphenhydramine and terfenadine. Pharmakopsychiat, 1979; 12: 35-44.
  40. Franks HM, Hensley VR, Hensley WJ, Starmer GA, Teo RKC. The interaction between ethanol and antihistamines: 1. dexchlorpheniramine. Med J Aust , 1978; 1: 449-452.
  41. Franks HM, Hensley VR, Hensley WJ, Starmer GA, Teo RKC. The interaction between ethanol and antihistamines: 2. clemastine. Med J Aust , 1979; 1: 185-186.
  42. Gaillard AWK, Gruisen A, de Jong R. The influence of antihistamines on human performance. Eur J Clin Pharmacol, 1988; 35: 249-253.
  43. Gengo FM, Dabronzo J, Yurchak A, Love S, Miller JK. The relative antihistaminic and psychomotor effects of hydroxyzine and cetirizine. Clin Pharmacol Ther, 1987; 42: 265-272.
  44. Gengo FM, Gabos C, Mechtler L. Quantitative effects of cetirizine and diphenhydramine on mental performance measured using an automobile driving simulator. Ann Allergy , 1990; 64: 520-526.
  45. Goetz DW, Jacobson JM, Murnane JE, Reid MJ, Repperger DW, et al. Prolongation of simple and choice reaction times in a double-blind comparison of twice-daily hydroxyzine versus terfenadine. J Allergy Clin Immunol , 1989; 84: 316-322.
  46. Goetz DW, Jacobson JM, Apaliski SJ, Repperger DW, Martin ME. Objective antihistamine side effects are mitigated by evening dosing of hydroxyzine. Ann Allergy , 1991; 67: 448-454.
  47. Goldstein L, Murphree HB, Pfeiffer CC. Comparative study of EEG effects of antihistamines on normal volunteers. J Clin Pharmacol , 1968; 8: 42-53.
  48. Hamilton H, Bush M, Bye C, Peck AW. A comparison of triprolidine and cyclizine on histamine (H1) antagonism, subjective effects and performance tests in man. Br J Clin Pharmacol , 1982; 13: 441-444.
  49. Hindmarch I. The effects of the sub-chronic administration of an antihistamine, clemastine, on tests of car driving ability and psychomotor performance. Curr Med Res Opin , 1976; 4: 197-206.
  50. Hindmarch I, Parrott AC. A repeated dose comparison of the side effects of five antihistamines on objective assessments of psychomotor performance, CNS arousal and subjective appraisals of sleep and early morning behaviour. Arzneimittelforschung/Drug Res, 1978; 28: 483-486.
  51. Hindmarch I, Easton JC. A placebo-controlled assessment of mequitazine and astemizole in tests of psychomotor ability. Int J Clin Pharmacol Res, 1986; 6: 457-464.
  52. Hindmarch I, et al. Psychomotor effects of astemizole and chlorpheniramine, alone and in combination with alcohol. Int Clin Psychopharmacol, 1987; 2: 117-119.
  53. Hopes H, Meuret GH, Ungethüm W, Leopold G, Wiemann H. Placebo controlled comparison of acute effects of ebastine and clemastine on performance and EEG. Eur J Clin Pharmacol , 1992; 42: 55-59.
  54. Hughes FW, Forney RB. Comparative effect of three antihistaminics and ethanol on mental and motor performance. Clin Pharmacol Ther, 1964; 5: 414-421.
  55. Irving A, Jones W. Methods for testing impairment of driving due to drugs. Eur J Clin Pharmacol , 1992; 43: 61-66.
  56. Katz IR, Sands LP, Bilker W, DiFilippo S, Boyce A, et al. Identification of medications that cause cognitive impairment in older people: the case of oxybutynin chloride. J Am Geriatr Soc, 1998; 46: 8-13.
  57. Kay GG, Berman B, Mockoviak SH, Morris CE, Reeves D, et al. Initial and steady-state effects of diphenhydramine and loratadine on sedation, cognition, mood, and psychomotor performance. Arch Intern Med, 1997; 157: 2350-2356.
  58. Kerr JS, Dunmore C, Hindmarch I. The psychomotor and cognitive effects of a new antihistamine, mizolastine, compared to terfenadine, triprolidine and placebo in healthy volunteers. Eur J Clin Pharmacol , 1994; 47: 331-335.
  59. Khosla PP, Saha N, Koul A, Chakrabarti A, Sankaranarayanan A, et al. Effects of ranitidine alone and in combination with chlorpheniramine on histamine-induced wheal and flare and psychomotor performance. Indian J Physiol Pharmacol, 1993; 37: 132-134.
  60. Kohl RL, Homick JL, Cintron N, Calkins DS. Lack of effects of astemizole on vestibular ocular reflex, motion sickness, and cognitive performance in man. Aviat Space Environ Med , 1987; 58: 1171-1174.
  61. Kulshrestha VK, Gupta PP, Turner P, Wadsworth J. Some clinical pharmacological studies with terfenadine, a new antihistamine drug. Br J Clin Pharmacol, 1978; 6: 25-29.
  62. Ledin T, Odkvist LM, Moller C. Effects of loratadine on postural control. Acta Otolaryngol (Stockh) , 1995; 520 (Suppl): 310-312.
  63. Lee A, Lader M, Kitler ME. The psychopharmacological effects of single doses of prolonged release formulations of dimethindene and chlorpheniramine in human volunteers. Human Psychopharmacol,
    1988; 3: 111-117.
  64. Levander S, Hagermark O, Stahle M. Peripheral antihistamine and central sedative effects of three H1-receptor antagonists. Eur J Clin Pharmacol, 1985; 28: 523-529.
  65. Levander S, Stahle-Backdahl M, Hagermark O. Peripheral antihistamine and central sedative effects of single and continuous oral doses of cetirizine and hydroxyzine. Eur J Clin Pharmacol, 1991; 41: 435-439.
  66. Lines C, Traub M, Raskin S, Mant T, Reines S. Lack of sedative and cognitive effects of diphenhydramine and cyclobenzaprine in elderly volunteers. J Psychopharmacol, 1997; 11:325-329.
  67. Linnoila M. Effects of antihistamines, chlormezanone and alcohol on psychomotor skills related to driving. Eur J Clin Pharmacol, 1973; 5: 247-254.
  68. Mattila MJ, Mattila M, Konno K. Acute and subacute actions on human performance and interactions with diazepam of temelastine (SK&F93944) and diphenhydramine. Eur J Clin Pharmacol , 1986; 31: 291-298.
  69. Meador KJ, Loring DW, Thompson EE, Thompson WO. Differential cognitive effects of terfenadine and chlorpheniramine. J Allergy Clin Immunol , 1989; 84: 322-325.
  70. Mohs RC, Tinklenberg JR, Roth WT, Kopell BS. Methamphetamine and diphenhydramine effects on the rate of cognitive processing. Psychopharmacol, 1978; 59:13-19.
  71. Moser L, Hüther KJ, Koch-Weser J, Lundt PV. Effects of terfenadine and diphenhydramine alone or in combination with diazepam or alcohol on psychomotor performance and subjective feelings. Eur J Clin Pharmacol , 1978; 14: 417-423.
  72. Moser L, Gerdes H, Beckmann M, Hopman G. Antihistamines and reactivity. Arzneimittelforschung/Drug Res, 1983; 33: 262-265.
  73. Moskowitz H, Burns M. Effects of terfenadine, diphenhydramine and placebo on skills performance. Cutis, 1988; 42: 14 -18.
  74. Murri L, Massetani R, Krause M, Dragonetti C, Iudice A. Evaluation of antihistamine-related daytime sleepiness; a double-blind, placebo-controlled study with terfenadine. Allergy, 1992; 47: 532-534.
  75. Neves-Pinto RM, et al.,Neves-Pinto RM, Lima GM, Teixeira RD. A double-blind study of the effects of loratadine versus placebo on the performance of pilots. Am J Rhinology , 1992; 6: 23-27.
  76. Nicholson AN. Effects of the antihistamines, brompheniramine maleate and triprolidine hydrochloride, on performance in man. Br J Clin Pharmacol, 1979; 8: 321-324.
  77. Nicholson AN, Stone BM. Performance studies with the H1-histamine receptor antagonists, astemizole and terfenadine. Br J Clin Pharmacol , 1982; 13: 199-202.
  78. Nicholson AN, Smith PA, Spencer MB. Antihistamines and visual function: studies on dynamic acuity and the pupillary response to light. Br J Clin Pharmacol, 1982; 14: 683-690.
  79. Nicholson AN, Stone BM. The H1-antagonist mequitazine: studies on performance and visual function. Eur J Clin Pharmacol, 1983; 25: 563-566.
  80. 80. Nicholson AN, Stone BM. The H2-antagonists, cimetidine and ranitidine: studies on performance. Eur J Clin Pharmacol, 1984; 26: 579-582.
  81. Nicholson AN, Pascoe PA, Stone BM. Histaminergic systems and sleep; studies in man with H1 and H2 antagonists. Neuropharmacology, 1985; 24: 245-250.
  82. Nicholson AN, Stone BM. Antihistamines: impaired performance and the tendency to sleep. Eur J Clin Pharmacol, 1986; 30: 27-32.
  83. Nicholson AN, Pascoe PA, Turner C, Ganellin CR, Greengrass PM, et al. Sedation and histamine H1-receptor antagonism: studies in man with the enantiomers of chlorpheniramine and dimethindene. Br J Pharmacol , 1991; 104: 207-276.
  84. Nicholson AN, Turner C. Central effects of the H1-antihistamine, cetirizine. Aviat Space Environ Med, 1998; 69: 166-171.
  85. Offenloch K, Zahner G. Rated performance, cardiovascular and quantitative EEG parameters during simulated instrument flight under the effect of terfenadine. Arzneimittelforschung/Drug Res, 1992; 42: 864-868.
  86. O'Hanlon JF. Antihistamines and driving safety. Cutis, 1988; 42: 10-13.
  87. Patat A, Gram LF, Dubruc C, Brohier S, Cabanis MJ, et al. Effects of mizolastine, a new antihistamine, on psychomotor performance and memory in elderly subjects. Int Clin Psychopharmacol, 1994; 9: 101-108.
  88. Patat A, Stubbs D, Dunmore C, Ulliac N, Sexton B, et al. Lack of interaction between two antihistamines, mizolastine and cetirizine, and ethanol in psychomotor and driving performance in healthy subjects. Eur J Clin Pharmacol, 1995; 48: 143-150.
  89. Pechadre JC, Vernay D, Trolese JF, Bloom M, Dupont P, et al. Comparison of the central and peripheral effects of cetirizine and terfenadine. Eur J Pharmacol, 1988; 35: 255-259.
  90. Pechadre JC, Beudin P, Eschalier A, Trolese JF, Rihoux JP. A comparison of central and peripheral effects of cetirizine and loratadine. J Int Med Res, 1991; 19: 289-295.
  91. Peck AW, Fowle ASE, Bye C. A comparison of triprolidine and clemastine on histamine antagonism and performance tests in man: implications for the mechanism of drug induced drowsiness. Eur J Pharmacol , 1975; 8: 455-463.
  92. Philpot EE, Brooker AE. Effects of sedating and nonsedating antihistamines on flying performance. Mil Med , 1993; 158: 654-660.
  93. Pishkin V, Sengel RA, Lovallo WR, Shurley JT. Cognitive and psychomotor evaluation of clemastine-fumarate, diphenhydramine HCI and hydroxyzine HCI: double-blind study. Cur Ther Res , 1983; 33: 230-237.
  94. Preston KL, Wolf B, Guarino JJ, Griffiths RR. Subjective and behavioral effects of diphenhydramine, lorazepam and methocarbamol: evaluation of abuse liability. J Pharmacol Exp Ther, 1992; 262: 707-720.
  95. Ramaekers JG, Uiterwijk MMC, O'Hanlon JF. Effects of loratadine and cetirizine on actual driving and psychometric test performance, and EEG during driving. Eur J Clin Pharmacol , 1992; 42: 363-369.
  96. Ramaekers JG, O'Hanlon JF. Acrivastine, terfenadine and diphenhydramine effects on driving performance as a function of dose and time after dosing. Eur J Clin Pharmacol , 1994; 47: 261-266.
  97. Reinberg A, Levi F, Guillet P, Burke JT, Nicolai A. Chronopharmacological study of antihistamines in man with special references to terfenadine. Eur J Clin Pharmacol , 1978; 14: 245-252.
  98. Rice VJ, Snyder HL. The effects of Benadryl and Hismanal on psychomotor performance and perceived performance. Aviat Space Environ Med , 1993; 64: 726-734.
  99. Riedel WJ, Shoenmakers EAJM, O'Hanlon JF. Loratadine and alcohol in combination: lack of interaction in an open road driving study. Alc Drug Traffic Safety - T89 , 1990; 483-488.
  100. Riedel WJ, van Veggel L, O'Hanlon JF. Cetirizine 10 and 20 mg impair psychomotor performance. Clin Exp Allergy , 1990; 20(Suppl 1): 97 [Abstract].
  101. Roehrs TA, Tietz EI, Zorick FJ, Roth T. Daytime sleepiness and antihistamines. Sleep , 1984; 7: 137-141.
  102. Roehrs TA, Claiborue D, Knox M, Roth T. Effects of ethanol, diphenhydramine, and triazolam after a nap. Neuropsychopharmacology , 1993; 9: 239-245.
  103. Roehrs TA, Zwyghuizen-Doorenbos A, Roth T. Sedative effects and plasma concentrations following single doses of triazolam, diphenhydramine, ethanol and placebo. Sleep , 1993; 16: 301-305.
  104. Rombaut N, Bhatti JZ, Curran S, Hindmarch I. Effects of topical administration of levocabastine on psychomotor and cognitive function. Ann Allergy , 1991; 67: 75-79.
  105. Roth T, Roehrs T, Koshorek G, Sicklesteel J, Zorick F. Sedative effects of antihistamines. J Allergy Clin Immunol, 1987; 80: 94-98.
  106. Saarialho-Kere U, Mattila MJ, Seppälä T. Psychomotor, respiratory and neuroendocrinological effects of a mu-opioid receptor agonist (oxycodone) in healthy volunteers. Pharmacol Toxicol, 1989; 65: 252-257.
  107. Saletu B, Grunberger J, Krupka M, Schuster P. Comparative double-blind placebo-controlled sleep laboratory studies of a combination of lorazepam and diphenhydramine (SM-1014) and its single components. Cur Ther Res , 1987; 42: 1037-1058.
  108. Sands L, Katz IR, DiFilippo S, D'Angelo K, Boyce A, et al. Identification of drug-related cognitive impairment in older individuals. Am J Geriatric Psychiat , 1997; 5:156-166.
  109. Schaffler K, Wauschkuhn C-H, Martinelli M, Rehn D, Brunnauer H. Influences of dimethindene maleate in a new formulation on oculo and psychomotor performance using the oculodynamic test (ODT) in volunteers. Agents Actions , 1994; 41: C136-C137.
  110. Schweitzer PK, Muehlbach MJ, Walsh JK. Sleepiness and performance during three-day administration of cetirizine or diphenhydramine. J Allergy Clin Immunol , 1994; 94: 716-724.
  111. Seidel WF, Cohen S, Bliwise NG, Dement WC. Cetirizine effects on objective measures of daytime sleepiness and performance. Ann Allergy , 1987; 59: 58-62.
  112. Seppälä T, Nuotto E, Korttila K. Single and repeated dose comparison of three antihistamines and phenylpropanolamine: psychomotor performance and subjective appraisals of sleep. Br J Clin Pharmacol , 1981; 12: 179-188.
  113. Seppälä T, Savolainen K. Effect of astemizole on human psychomotor performance. Curr Ther Res, 1982; 31: 638-644.
  114. Simons FE, Fraser TG, Reggin JD, Simons KJ. Comparison of the central nervous system effects produced by six H1-receptor antagonists. Clin Exp Allergy, 1996; 26: 1092-1097.
  115. Simons KJ, Dilay DJ, Reggin JD, Fraser TG, Patrick JP, Simons FER. Cetirizine (C), hydroxyzine (H), and diphenhydramine (D): studies of central nervous system (CNS) effects using the P300-event-related potential (P300). J Allergy Clin Immunol , 1994; 93: 235 [Abstract].
  116. Spector R, Choudhury AK, Chiang C, Goldberg MJ, Ghoneim MM. Diphenhydramine in Orientals and Caucasians. Clin Pharmacol Ther, 1980; 28: 229-234.
  117. 117. Swire FMM, Marsden CA, Barber C, Birmingham AT. Effects of a sedative and of a non-sedative H1-antihistamine on the event-related potential (ERP) in normal volunteers. Psychopharmacology , 1989; 98: 425-429.
  118. Tharion WJ, Kobrick JL, Lieberman HR, Fine BJ. Effects of caffeine and diphenhydramine on auditory evoked cortical potentials. Percept Mot Skills , 1993; 76: 707-715.
  119. Tharion WJ, McMenemy DJ, Rauch TM. Antihistamine effects on the central nervous system, cognitive performance, and subjective states. Neuropsychobiology, 1994; 29: 97-104.
  120. Unchern S, Chumsawat P, Sriwatanakul K, Limsuwan A. Psychomotor performances and subjective feeling studies with antihistamine. J Med Assoc Thai, 1986; 69: 203-209.
  121. Valk PJ, Simons RM, Struyvenberg PA, Kruit H, van Berge Henegouwen MT. Effects of a single dose of loratadine on flying ability under conditions of simulated cabin pressure. Am J Rhinol, 1997; 11: 27-33.
  122. Vermeeren A, O'Hanlon JF. Fexofenadine's effects, alone and with alcohol, on actual driving and psychomotor performance. J Allergy Clin Immunol , 1998; 101: 306-311.
  123. Volkerts ER, Van Willigenburg APP, Van Laar MW, Maes RAA. Does cetirizine belong to the new generation of antihistamines? An investigation into its acute and subchronic effects on highway driving, psychometric test performance and daytime sleepiness. Human Psychopharmacology , 1992; 7: 227-238.
  124. Vuurman EF, Uiterwijk MMC, Rosenzweig P, O'Hanlon JF. Effects of mizolastine and clemastine on actual driving and psychomotor performance in healthy volunteers. Eur J Clin Pharmacol , 1994; 47: 253-259.
  125. Walsh JK, Muehlbach MJ, Schweitzer PK. Simulated assembly line performance following ingestion of cetirizine or hydroxyzine. Ann Allergy , 1992; 69: 195-200.
  126. Walsh JK, Muehlbach MJ, Humm T, Moss KL, Schweitzer PK. Sleepiness and performance during three days' use of cetirizine or diphenhydramine. J Allergy Clin Immunol , 1994; 93: 235 [Abstract].
  127. Wilkinson CJ, Moskowitz H. Acute effects of loratadine, diphenhydramine and placebo, alone and with alcohol, on skills performance. Alc Drugs Traffic Safety - T89, 1990; 476-482.
  128. Wilkinson CJ, Moskowitz H. A comparative study of the acute and chronic effects of loratadine, diphenhydramine and placebo, alone and with alcohol, on skills performance. SCRI Final Report for Schering (SC68-chronic dose); 1998, manuscript in preparation.
  129. Wilkinson CJ, Burns M, Korn S, Raskin S, Owens SC, Moskowitz H. A double-blind, multiple-dose, crossover, placebo-controlled study to investigate the effects of cyclobenzaprine, diphenhydramine and amitriptyline on driving-related psychomotor skills in young volunteers. Final Report for Merck (ME-128), 1998.
  130. Witek TJ, Jr., Canestrari DA, Miller RD, Yang JY, Riker DK. The effects of phenindamine tartrate on sleepiness and psychomotor performance. J Allergy Clin Immunol , 1992; 90: 953-961.
  131. Witek TJ, Jr., Canestrari DA, Miller RD, Yang JY, Riker DK. Characterization of daytime sleepiness and psychomotor performance following H1 receptor antagonists. Ann Allergy Asthma Immunol, 1995; 74: 419-426.
  132. Yasuda SU, Kay G, Sale M, Zannikos P, Eberle C, Woosley RL. Effect of low dose chlorpheniramine on cognitive function. Clin Pharmacol Ther, 1998; 63: 172 [Abstract].
  133. Comer SD, Haney M, Ward AS, Fischman MW, Foltin RW. Effects of methysergide and loratadine on food intake, mood, and performance of humans living in a residential laboratory. Physiol Behav, 1998; 64: 159-164.
  134. Scavone JM, Greenblatt DJ, Harmatz JS, Engelhardt N, Shader RI. Pharmacokinetics and pharmacodynamics of dipphenhydramine 25 mg in young and elderly volunteers. J Clin Pharmacol , 1998; 38: 603-609.